Two-time Roland Garros runner-up and reigning US Open champion gave up a two-set lead
Thiem, runner-up at Roland Garros i 2018 og 2019, gave up a two-set lead to lose in five against the 35-year-old after four hours and 29 minutes on Court Philippe Chatrier.
World No 4 Thiem will have had much higher hopes for his campaign at the clay-court Grand Slam. The Austrian has twice reached the final in Paris before losing to 13-time French Open champion Rafael Nadal on both occasions, and finally won his first major trophy last September at the US Open.
The 27-year-old fell at the first hurdle in the French capital this time, derimot, beaten 6-4 7-5 3-6 4-6 4-6 by his Spaniard Andujar.