Warren Gatland’s side kick off the Test series in Cape Town this weekend
All three games will now be held in the city with Covid-19 cases surging in Gauteng, where the Second Test and Third Test were due to be held.
The Lions arrive having been beaten just once during their warm-up fixtures after victory over the Stormers last Saturday.
Here is everything you need to know about the First Test:
The match will kick off at 5pm BST in Cape Town a on Saturday 10 juillet.
Comment puis-je le regarder?
Sky Sports will air the fixture live, with the action also available to stream on the broadcaster’s website and via the SkyGo app.
Quelle est l'actualité de l'équipe?
South Africa XV (1-15): Ox Nche, Bongi Mbonambi, Trevor Nyakane, Eben Etzebeth, Franco Mostert, Siya Kolisi (c), Pieter-Steph du Toit, Kwagga Smith; Faf de Klerk, Handre Pollard, Makazole Mapimpi, Damian de Allende, Lukhanyo Am, Cheslin Kolbe, Willie Le Roux
Replacements: Malcolm Marx, Steven Kitshoff, Frans Malherbe, Lood de Jager, Rynhardt Elstadt; Herschel Jantjies, Elton Jantjies, Damian Willemse
Lions XV (1-15): Wyn Jones, Luke Cowan-Dickie, Tadhg Furlong, Maro Itoje, Alun Wyn Jones (c), Courtney Lawes, Tom Curry, Jack Conan; Ali Price, Dan Biggar, Duhan van der Merwe, Robbie Henshaw, Elliot Daly, Anthony Watson, Stuart Hogg
Replacements: Ken Owens, Rory Sutherland, Kyle Sinckler, Tadhg Beirne, Hamish Watson; Conor Murray, Owen Farrell, Liam Williams
Afrique du Sud: Soirées
Afrique du Sud 23-18 Lions