The defeat ended the Suns’ franchise-record playoff winning streak at nine games.
The seven-time All-Star had to deliver after missing two important free throws in the one-point Game 2 loss and with team-mate Kawhi Leonard still out injured.
George embraced the challenge on Thursday by making six of seven free throws en route to scoring 27 as well as recording 15 rebounds and eight assists, as his side won 106-92.
The sides played a tight first half with Phoenix leading 48-46 at the break before the Clippers exploded with a 21-3 run in the third quarter that took them ahead 71-56.
The three points contributed in that run by the visitors came from Chris Paul who missed the first two games of the series due to the league’s health and safety protocols.
The former Clipper, who was booed during introductions at the Staples Center, scored 15 points and had 12 assists but was one of many Phoenix players plagued by inaccuracy as he went five of 19 from the field.
His team-mate Devin Booker was just five of 21 from the field and made only one of his seven three-point attempts to finish with 15 points.
The defeat ended the Suns’ franchise-record playoff winning streak at nine games, with the visitors leading the series 2-1 ahead of Game 4 in Los Angeles on Saturday.